Rab11a Mediates Vascular Endothelial-Cadherin Recycling and Controls Endothelial Barrier Function

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Rab11a Mediates Vascular Endothelial-Cadherin Recycling and Controls Endothelial Barrier Function.

OBJECTIVE Vascular endothelial (VE)-cadherin is the predominant component of endothelial adherens junctions essential for cell-cell adhesion and formation of the vascular barrier. Endocytic recycling is an important mechanism for maintaining the expression of cell surface membrane proteins. However, little is known about the molecular mechanism of VE-cadherin recycling and its role in maintenan...

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ژورنال

عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology

سال: 2016

ISSN: 1079-5642,1524-4636

DOI: 10.1161/atvbaha.115.306549